在COVID-19住院后3个月和12个月的CT异常以及与疾病严重程度的关联:一个前性队列研究
Trond Mogens Aaløkken1,2, Haseem Ashraf2,3, Gunnar Einvik2,4
1Department of Radiology and Nuclear Medicine, Oslo University Hospital Rikshospitalet, Oslo, Norway.
PloS one
|May 6, 2024
概括
胸部CT扫描显示,COVID-19住院治疗后3至12个月内,地面玻璃的不透明度和马赛克形状下降. 持续的不透明与最初的疾病严重程度和年龄的增加有关.
科学领域:
- 放射学 放射学是一门学科.
- 肺部病理学 肺部病理学
- 传染性疾病 传染性疾病
背景情况:
- 住院治疗COVID-19可能导致持续的肺部异常.
- 了解这些变化的时间演变对于患者管理至关重要.
研究的目的:
- 评估COVID-19住院治疗后3至12个月内胸部CT检测结果的变化.
- 为了确定这些CT变化和最初的疾病严重程度之间的关联.
主要方法:
- 对COVID-19患者进行长度队列研究.
- 胸部CT扫描在3个月和12个月使用CT严重性得分 (CSS) 进行分析.
- 多变量回归分析了缩写CSS的决定因素.
主要成果:
- 地面玻璃的不透明度 (GGO) 和马赛克主义在3至12个月之间显著下降.
- 在同一时期,对细胞带的增加.
- 在12个月内持续的GGO与更高的初始COVID-19严重程度 (WHO类别5-7) 和年龄≥60.7相关.
结论:
- 与COVID-19相关的肺部异常在12个月内演变.
- 最初的疾病严重程度和患者年龄是持续性GGO的关键因素.
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