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菌体控制活中的Vibrio alginolyticus在幼虫培养中使用它们之前的活

Amanda Dias Tadeu¹, João Duarte¹, David Trindade¹

¹Department of Biology and CESAM, University of Aveiro, Campus Universitário de Santiago, 3810-193 Aveiro, Portugal.

Journal of applied microbiology

|May 6, 2024

概括

两种细菌菌体,TDD和SRI,被评估用于控制盐水中的Vibrio alginolyticus. 菌体TDD在减少细菌负载方面表现出卓越的有效性,为水产养殖应用提供了一种安全的方法.

科学领域:

微生物学微生物学
水产养殖是水产养殖的一种方式.
细菌治疗疗法是一种细菌治疗.

背景情况:

菌Alginolyticus对水产养殖,特别是幼虫养殖构成重大威胁.
控制V. alginolyticus在像盐水这样的活物中对预防疾病爆发至关重要.
菌体为控制水产养殖中的细菌感染提供了抗生素的有希望的替代品.

研究的目的:

评估两种分离的细菌菌体 (TDD和SRI) 和它们的尾酒对抗Vibrio alginolyticus的疗效.
在幼虫培养中使用之前,评估盐水 (Artemia franciscana) 的菌体治疗的安全性和有效性.

主要方法:

针对V. alginolyticus的两个细菌菌体 (TDD和SRI) 的分离和表征.
在培养基和人造海洋水中进行体外无活化测定.
在盐水和周围的水中减少V. alginolyticus的菌体有效性的评估.
基因组分析以确认毒性和抗生素耐药性基因的缺失.

主要成果:

菌体TDD和SRI以及它们的尾酒都有效地减少了盐水和培养水中的V. alginolyticus负载.
与菌体SRI和尾酒相比,菌体TDD在培养基中显示出更高的无活化效率.
菌体并没有对盐水或其他Vibrio物种的自然微生物群产生负面影响.
基因组分析证实了菌体的安全性,缺乏毒性或抗生素耐药性基因.

结论:

菌体TDD和SRI是控制盐水中的V. alginolyticus的安全和有效药物.
菌体应用是减轻水产养殖活中的V. alginolyticus污染的可行策略.
这种方法支持开发可持续的无抗生素水产养殖实践.

关键词:

这种病毒是Vibrio alginolyticus.水产养殖的水产养殖细菌菌体是一种细菌体.盐水的鱼是没有的.菌体的生物控制

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