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Updated: Jun 27, 2025

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解读FADD-procaspase-8-cFLIP复合体中的DED组装机制,这些复合体调节了亡

Chao-Yu Yang1, Chia-I Lien2, Yi-Chun Tseng1,3

  • 1Genomics Research Center, Academia Sinica, Taipei, 11529, Taiwan.

Nature communications
|May 6, 2024
PubMed
概括

对FADD, procaspase-8和cFLIP复合体的结构洞察力揭示了这些蛋白质如何调节细胞死亡途径. 原子结构阐明了控制亡和亡信号发育和疾病的机制.

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