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相关概念视频

¹³C NMR: ¹H–¹³C Decoupling01:04

¹³C NMR: ¹H–¹³C Decoupling

1.1K
The probability of having two carbon-13 atoms next to each other is negligible because of the low natural abundance of carbon-13. Consequently, peak splitting due to carbon-carbon spin-spin coupling is not observed in spectra. However, protons up to three sigma bonds away split the carbon signal according to the n+1 rule, resulting in complicated spectra.
A broadband decoupling technique is used to simplify these complex, sometimes overlapping, signals. Broadband decoupling relies on a...
1.1K
¹³C NMR: Distortionless Enhancement by Polarization Transfer (DEPT)01:20

¹³C NMR: Distortionless Enhancement by Polarization Transfer (DEPT)

1.0K
When proton-coupled carbon-13 spectra are simplified by a broadband proton decoupling technique, structural information about the coupled protons is lost. Distortionless enhancement by polarization transfer (DEPT) is a technique that provides information on the number of hydrogens attached to each carbon in a molecule. While the DEPT experiment utilizes complex pulse sequences, the pulse delay and flip angle are specifically manipulated. The resulting signals have different phases depending on...
1.0K
Carbon-13 (¹³C) NMR: Overview01:10

Carbon-13 (¹³C) NMR: Overview

5.6K
Carbon-13 is a naturally occurring NMR-active isotope of carbon with a low natural abundance of 1.1%. In contrast, carbon-12 is the most abundant isotope of carbon with zero nuclear spin. Therefore, it is NMR inactive. The gyromagnetic ratio of carbon-13 is smaller than that of protons. As a result, carbon-13 resonance is about 6000 times weaker than proton resonance. For a given magnetic field strength, the resonance frequency of carbon-13 is about one-fourth of the resonance frequency for...
5.6K

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相关实验视频

Updated: Jun 27, 2025

Hyperpolarized 13C Metabolic Magnetic Resonance Spectroscopy and Imaging
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数据格式标准化和DICOM集成用于超极化C MRI13

Ernesto Diaz1, Renuka Sriram1, Jeremy W Gordon1

  • 1Department of Radiology and Biomedical Imaging, University of California - San Francisco, San Francisco, CA, USA.

Journal of imaging informatics in medicine
|May 6, 2024
PubMed
概括

标准化对超极化 (HP) 13CMRI的数据存储对于在不同研究场所比较结果至关重要. 这项研究提出了一个最小的数据集,并使用DICOM标准对HP13CMRI数据存储进行演示.

关键词:
这是一个DICOM格式.实验的元数据是实验的元数据.超极化13C核磁共振成像 (MRI) 是一种超极化13C核磁共振成像.代谢成像成像 - 代谢成像

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Multi-modal Pulmonary Imaging: Using Complementary Information from CT and Hyperpolarized 129Xe MRI to Evaluate Lung Structure-Function
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科学领域:

  • 医疗成像医学成像
  • 代谢成像 - 代谢成像
  • 磁共振成像是一种磁共振成像技术.

背景情况:

  • 超极化 (HP) 13CMRI是体内代谢测量的一个有前途的技术.
  • 目前在多个全球研究站点进行人体试验,需要标准化数据实践.
  • 跨站点进行有意义的数据比较需要一致的数据存储协议.

研究的目的:

  • 定义HP13CMRI研究的最低数据集.
  • 为了证明使用医学数字成像和通信 (DICOM) 标准对HP13CMRI数据的利用.
  • 为HP13CMRI数据存储提出最佳实践,以支持多站点协作和技术进步.

主要方法:

  • 描述HP13CMRI的基本数据元素.
  • 调整现有的DICOM属性,特别是"对比度/波力"模块,以适应HP13C MRI特定信息.
  • 开发和演示用于使用各种脉冲序列创建DICOM对象的管道,用于人类和动物的HP13C MRI研究.
  • 使用基于Python的方法来修改DICOM对象以获得独特的HP13CMRI数据,而不是标准管道所涵盖的.

主要成果:

  • 为HP13CMRI研究量身定制的建议最低信息集.
  • 在DICOM标准中集成HP13CMRI数据的可行性,包括代理信息和光谱/代谢物维度.
  • 成功实施了用于各种HP13CMRI成像场景的DICOM对象创建和修改管道.
  • 对基于Python的方法进行有效的DICOM对象增强的验证.

结论:

  • DICOM标准提供了存储独特的HP13CMRI数据的灵活性,包括代谢和光谱信息.
  • 使用DICOM的标准化数据存储是可以实现的,对于多站点HP13CMRI研究的增长和可比性至关重要.
  • 拟议的方法和最佳实践将促进未来的多站点试验,研究工作和HP13C MRI的技术开发.