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Updated: Jun 27, 2025

Molecular Analysis of Endothelial-mesenchymal Transition Induced by Transforming Growth Factor-β Signaling
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通过miR27a抑制YTHDF2-介导的m6A甲基化,作为BMSCs中对激素骨硬化的保护机制

Tianyi Yuan1, Hongjiang Liu1, Maimaitiyibubaji Abudoukadier1

  • 1The Fifth Clinical Medical College of Xinjiang Medical University, Xinjiang Uygur Autonomous Region, Urumqi, 830011, China.

BMC musculoskeletal disorders
|May 6, 2024
PubMed
概括

微RNA 27a (miR27a) 通过向含有YTH域的蛋白2 (YTHDF2) 来调节骨髓中酶干细胞 (BMSC) 的分化. 这种相互作用影响N6-甲基氨酸 (m6A) 甲基化,并促进骨质生成,为类固醇诱导的股骨头缩 (SNFH) 提供了潜在的治疗策略.

关键词:
骨髓中介细胞干细胞是骨髓中介细胞的干细胞.这是一种N6-甲基氨酸.股骨头的类固醇诱导的亡.这是一个小RNARNA.

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