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各种负载大小对ACL的影响:使用青少年猪关节的体外研究

Jason Koh¹, Nirav Mungalpara², Sunjung Kim²

¹Institute of Orthopaedics and Spine, Department of Orthopaedic Surgery, Northshore University HealthSystem, 9669 Kenton Avenue, Suite 305, Skokie, IL, 60076, USA.

Journal of orthopaedic surgery and research

|May 6, 2024

概括

青少年前十字带 (ACL) 损伤正在上升. 这项研究验证了猪关节作为年轻人ACL生物力学研究的模型,显示较高的负载增加ACL应变并降低性.

科学领域:

整形外科整形外科整形外科
生物力学生物力学
运动医学运动医学

背景情况:

青少年前十字带 (ACL) 损伤越来越令人担忧.
在青少年中研究ACL生物力学是具有挑战性的,因为有限的尸体样本.
青少年猪关节被提出为ACL研究的合适模型.

研究的目的:

为了验证青少年猪关节作为ACL生物力学研究的模型.
为了研究猪ACL对不同周期负荷的生物力学反应.
为了在不同的负载条件下比较ACL应变和刚性.

主要方法:

在30只猪 (2-4个月大) 的关节上进行了实验.
接头经过负载到故障测试或100个周期的300N或520N力.
测量和统计分析了ACL应变,负载到故障和度.

主要成果:

较高的负载 (520N) 导致较大的ACL应变,并且与较低的负载 (300N) 相比,负载到故障的显著减少.
在循环负荷后,ACL度显著下降,特别是520N (86.90N/mm) 与对照组 (152.46N/mm) 相比.
在520N组的破裂模式模仿了青少年的ACL损伤.

结论:

青少年猪关节是研究骨不成熟个体的ACL生物力学的一个合适的模型.
这项研究强调了ACL对高冲击体育相关负载的易感性.
建议对各种负载场景和肌肉协同激活在伤害预防中的作用进行进一步的研究.

关键词:

在ACL硬度.负载到故障的时间.猪 ACL 的情况.在ACL的菌株.

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