DDID:用于可视化和分析饮食与药物相互作用的全面资源
Yanfeng Hong1, Hongquan Xu1, Yuhong Liu1
1Key Laboratory of Elemene Class Anti-cancer Chinese Medicines, School of Pharmacy, Hangzhou Normal University, Hangzhou 311121, China.
Briefings in bioinformatics
|May 7, 2024
概括
一个新的在线平台,饮食药物相互作用数据库 (DDID),详细介绍了食物和草药如何与药物相互作用. 本资源有助于理解饮食与药物相互作用 (DDI),以提高药物安全性和利用率.
科学领域:
- 药理学 药理学是指药理学的学科.
- 营养科学 营养科学
- 生物信息学是一种生物信息学.
背景情况:
- 饮食与药物相互作用 (DDI) 显著影响药物的生物可用性和药理动力学.
- 了解DDI对于公共卫生和患者安全至关重要.
- 需要对DDI的系统资源,以将饮食成分与药物作用相关联.
研究的目的:
- 建立一个全面的,公开可访问的在线平台,详细介绍饮食与药物相互作用.
- 系统地列出DDI的相关性和机制.
- 为药物利用和组合研究提供一个有价值的资源.
主要方法:
- 开发了饮食药物相互作用数据库 (DDID) 在线平台.
- 汇编了1338种食品/草药和1516种药物的数据.
- 收集和分类了23,950个交互记录,将它们评价为积极,消极,无效,有害或可能.
- 整合到其他相关数据库的交叉链接.
主要成果:
- 现在可以在https://bddg.hznu.edu.cn/ddid/.上公开访问DDID平台.
- 该数据库包含有关食品,草药,药物及其相互作用的大量信息.
- 互动被仔细审查和分类,提供细微的评估.
结论:
- DDID是理解食物,草药和药物之间的复杂关系的关键资源.
- 该平台促进了药物利用的增强,并支持对药物组合的研究.
- DDID承诺通过突出潜在的饮食药物相互作用来提高患者的安全性.
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