在急性心肌梗塞患者中,肺高血压的预后值与nomogram在急性心肌梗塞患者中具有左心室功能减弱的预后值
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Myocardial Infarction and Functional Outcome Assessment in Pigs
Published on: April 25, 2014
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Qian Liu1, Changying Zhao1, Peizhu Dang2
1Department of Cardiovascular Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Frontiers in cardiovascular medicine
|May 7, 2024
概括
肺高血压 (PH) 在急性心肌梗塞 (AMI) 患者的1年死亡率显著增加,左心室功能受损. 结合PH的新名图可以预测死亡风险.
科学领域:
- 心脏病学 心脏病学
- 肺部医学 肺部医学
- 临床研究 临床研究
背景情况:
- 肺高血压 (PH) 是急性心肌梗塞 (AMI) 的已知预后因素.
- 在左心室功能减弱的患者中,PH对AMI预后的影响可能会被放大.
研究的目的:
- 为了研究PH对AMI患者的1年死亡率的影响,AMI患者的左心室功能减弱.
- 在这个患者群体中确定1年死亡率的独立风险因素.
- 开发1年死亡率的预测模型.
主要方法:
- 对左心室功能减弱的AMI患者进行回顾性队列研究 (2018年1月至2022年1月).
- 患者被分为PH和对照组,根据心声回声仪评估的缩性肺动脉压.
- 倾向分数匹配 (PSM) 用于在不同组之间平衡基线特征.
主要成果:
- 在PSM之后,分析了504名患者 (每组252名).
- 与对照组 (5.3%) 相比,PH组的1年死亡率明显高 (15.5%).
- PH,左心室喷射率降低,肌酸激酶-MB升高,以及脑前尿素升高被确定为1年死亡率的独立风险因素.
结论:
- 同时使用PH与AMI患者的1年死亡率增加有关,AMI患者的左心室功能减弱.
- 为了估计1年死亡风险,开发了一种包含包括PH在内的四个独立风险因素的预测性名录.
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