进入食道并发症的旅程:用尖端内镜,计量仪和门诊pH研究解码系统性硬化症
Omer Ahmed Hamad Amin1, Raouf Rahim Mirza2, Hiwa Abubakr Hussein2
1Department of Rheumatology, Ranya Teaching Hospital, Ministry of Health, Ranya, Kurdistan Region, Iraq.
International journal of general medicine
|May 7, 2024
概括
系统性硬化症 (SSc) 通常影响食道,女性经历更多的症状,如胃灼热和消化不良. 侵蚀性GERD是SSc患者这些食道问题的关键风险因素.
科学领域:
- 胃肠病学 胃肠病学
- 类风湿病学 类风湿病学
- 内部医学 内部医学
背景情况:
- 系统性硬化症 (SSc) 是一种罕见的自身免疫性疾病,影响结缔组织,导致纤维化和血管病变.
- 食道功能障碍是SSc的常见并发症,影响了相当一部分患者.
- 了解这些食道表现对于患者管理至关重要.
研究的目的:
- 突出系统性硬化症 (SSc) 患者食道干扰的特征和临床症状.
- 调查SSc患者队列中食道并发症的流行率和性质.
- 在SSc.中识别与食道功能障碍相关的风险因素.
主要方法:
- 一项涉及26名被诊断为SSc患者的研究在伊拉克苏莱曼尼亚市进行.
- 通过食道测量,食道胃管腺镜 (EGD) 和24小时阻抗-pH监测来评估食道干涉.
- 数据收集发生在2022年11月至2023年8月期间.
主要成果:
- 报告症状的女性占主导地位,胃灼热率高 (76.9%),消化不良 (76.9%),水刷 (73.1%),吐 (69.2%).
- 在69.2%的患者中通过EGD观察到侵蚀性胃肠道逆流病 (GERD).
- 食道测量显示食道下关节压力下降 (76.9%) 和周围收缩 (76.9%),而84.6%的pH监测显示反流.
- 侵蚀性GERD显著增加了缺食症 (OR=3.482) 和吐 (OR=4.030) 的风险.
结论:
- 性别特定的因素对于诊断和管理SSc.的食道并发症很重要.
- 全面的诊断评估对于检测食道参与SSc.至关重要.
- 侵蚀性GERD是SSc患者发展食障碍和吐的重要危险因素.
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