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RAG可以抑制2组先天性淋巴细胞

Aaron M Ver Heul1, Madison Mack2, Lydia Zamidar3,4,5,6

  • 1Division of Allergy and Immunology, Department of Medicine, Washington University School of Medicine, St. Louis, MO 63130, USA.

bioRxiv : the preprint server for biology
|May 7, 2024
PubMed
概括

重组酶激活基因 (RAG) 抑制先天性淋巴细胞 (ILCs),揭示了在2型免疫中发挥的新作用. 在小鼠中RAG缺乏导致扩大ILC2s和在亚托皮性皮炎模型中增加炎症.

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