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Updated: Jun 27, 2025

Investigating Tissue- and Organ-specific Phytochrome Responses using FACS-assisted Cell-type Specific Expression Profiling in Arabidopsis thaliana
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预测Arabidopsis thaliana的基因表达对环境的反应,使用DNA序列的自然变异

Margarita Takou1, Emily S Bellis1,2, Jesse R Lasky1

  • 1Pennsylvania State University, University Park, 16802, USA.

bioRxiv : the preprint server for biology
|May 7, 2024
PubMed
概括

机器学习模型在预测Arabidopsis thaliana寒冷反应中的基因表达变化方面取得了适度的成功. 需要进一步开发,以充分捕捉环境适应的 cis-regulatory 基因型-表型映射的复杂性.

关键词:
进化 演化 演化 演化 演化 演化 演化 演化基因表达 预测 基因表达基因型到表型的地图.低频变体的低频变体机器学习是机器学习.监管要素 监管元素 监管元素

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Transcription01:10

Transcription

Overview
Transcription is the process of synthesizing RNA from a DNA sequence by RNA polymerase. It is the first step in producing a protein from a gene sequence. Additionally, many other proteins and regulatory sequences are involved in the proper synthesis of messenger RNA (mRNA). Regulation of transcription is responsible for the differentiation of all the different types of cells and often for the proper cellular response to environmental signals.
Transcription Can Produce Different Kinds...
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Gene expression is a dynamic process that is significantly influenced by environmental factors. This interaction underlies the complex nature of biological development and the phenotypic differences observed among individuals, even among those with identical genetic makeups. Factors such as radiation, temperature, behavior, nutrition, and stress play pivotal roles in determining how genes are expressed. The concept of the reaction range is central to understanding this interaction. It posits...
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Reporter Genes02:11

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In 1928, a German botanist Emil Heitz observed the moss nuclei with a DNA binding dye. He observed that while some chromatin regions decondense and spread out in the interphase nucleus, others do not. He termed them euchromatin and heterochromatin, respectively. He proposed that the heterochromatin regions reflect a functionally inactive state of the genome. It was later confirmed that heterochromatin is transcriptionally repressed, and euchromatin is transcriptionally active chromatin.
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