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Updated: Jun 27, 2025

Using X-ray Crystallography, Biophysics, and Functional Assays to Determine the Mechanisms Governing T-cell Receptor Recognition of Cancer Antigens
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探索基于结构的深度学习方法对T细胞受体设计的潜力

Helder V Ribeiro-Filho1, Gabriel E Jara1, João V S Guerra1,2

  • 1Brazilian Biosciences National Laboratory, Brazilian Center for Research in Energy and Materials, Campinas 13083-100, Brazil.

bioRxiv : the preprint server for biology
|May 7, 2024
PubMed
概括

深度学习模型在设计T细胞受体 (TCRs) 用于癌症免疫治疗方面表现有前途. 这些计算方法比传统的工程 TCR 针对特定的方法有优势.

关键词:
深度学习是一种深度学习.蛋白质的设计 蛋白质的设计T细胞受体受体的 T 细胞受体.

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Antigen receptors are essential components of the immune system crucial in defending the body against foreign invaders. These receptors are present on the surface of B and T cells, enabling them to recognize antigens and mount an appropriate immune response.
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