SUMOylation的向导致cBAF复杂的稳定和破坏SS18::SSX转录组在Synovial Sarcoma中的转录组

概括

用TAK-981向SUMOylation通路通过恢复染色体重塑复合物来抑制突肉瘤 (SS). 这种方法显示出SS治疗的希望,并与化疗协同作用.

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