体重指数 (BMI) 与释放乙凝 (ENG) 的植入物连续性之间的关联
Aya Mohr-Sasson1,2, Leanne Dalal1, Asha Bhalwal1
1Advanced Minimally Invasive Gynecologic Surgery, Department of Obstetrics, Gynecology and Reproductive Sciences, McGovern Medical School at The University of Texas Health Science Center, Houston, Texas, USA.
概括
副作用,而不是身体质量指数 (BMI),与早期移除乙格斯特植入物有关. 非肥胖女性报告了更多的副作用,影响了治疗的坚持.
科学领域:
- 生殖健康 生殖健康
- 避孕药是一种避孕药,用于避孕.
- 肥胖医学 肥胖医学
背景情况:
- 释放etonogestrel的植入物是一种高效的长效可逆避孕药,推使用三年.
- 不规律的出血,体重增加和是停止使用这种避孕方法的主要原因.
- 了解影响坚持的因素,如体重指数 (BMI),对于优化避孕使用至关重要.
研究的目的:
- 调查身体质量指数 (BMI) 与使用乙格斯特勒植入物的副作用发生率之间的关联.
- 为了确定BMI是否影响对乙格斯特植入物治疗的坚持.
- 为了识别早期植入物切除的预测因素.
主要方法:
- 一项回顾性队列研究包括1318名女性,在2019年1月至2021年12月期间接受了etonogestrel植入物插入.
- 关于人口统计,病史和随访的数据从电子医疗记录中收集.
- 主要结局是不同肥胖类别的植入物移除率,使用多回归后勤分析进行统计分析.
主要成果:
- 35%的女性要求提前切除植入物,不规则出血是最常见的原因.
- 与完成整个治疗时间的女性相比,要求提前切除的女性肥胖率 (BMI ≥30) 较低.
- 副作用的存在,而不是BMI,是唯一与早期植入物切除相关的独立预测因素 (P=0.04).
结论:
- 坚持使用乙格斯特勒植入式避孕药与副作用的发生有关.
- 不肥胖的女性更频繁地报告了需要提前切除的副作用.
- 身体质量指数 (BMI) 并未被确定为影响依从乙格斯特植入物治疗的重要因素.
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