在患有不复杂感染的住院儿童中增加肠道抗生素的使用
Matthew J Molloy1,2,3, Calli Morris4, Alicia Caldwell1,3
1Divisions of Hospital Medicine.
Pediatrics
|May 7, 2024
概括
将住院儿童从静脉注射转移到肠道抗生素改善了护理. 这项研究增加了肠道抗生素的使用,降低了成本和常见感染的IV导管使用.
科学领域:
- 儿童传染病 儿童传染病
- 抗微生物药物管理委员会
- 改善医疗保健质量 改善医疗保健质量
背景情况:
- 在抗微生物药物管理中,服用途径是关键.
- 在儿童中,从静脉注射到肠道抗生素的早期过渡可以减少不良事件,成本和停留时间.
- 这项研究重点关注住院儿童的不复杂常见细菌感染.
研究的目的:
- 在6个月内将医院医学患者的肠道抗生素剂量的百分比从50%提高到80%的不复杂的常见细菌感染.
- 评估干预措施对抗生素施用途径的影响.
- 改善患者的治疗结果,降低医疗保健成本.
主要方法:
- 一个多学科团队利用计划-做-研究-行动循环进行干预设计.
- 干预措施包括提供者教育,团队聚集讨论和印刷信息材料.
- 主要指标是肠道抗生素剂量的百分比;次要指标包括成本,静脉导管使用,停留时间和再入院.
主要成果:
- 在研究期间,肠道抗生素剂量的百分比从50%增加到67%.
- 抗生素成本和周围静脉导管使用每次遇到下降.
- 没有观察到停留时间或7天再接收率的重大变化.
结论:
- 在患有常见细菌感染的住院儿童中,可以提高肠道抗生素剂量.
- 专注于文化变革和沟通的干预措施导致了持续的改善.
- 这些发现支持适合的儿科患者早期过渡到肠道抗生素.
相关概念视频
Antibiotic Selection
53.2K
Overview
53.2K
Enteral Nutrition II: Nasointestinal and Gastrostomy Feeding
117
Enteral nutrition encompasses various methods of delivering nutrition directly to the gastrointestinal (GI) tract, bypassing traditional oral intake. It is particularly beneficial for patients who cannot eat by mouth but have a functioning digestive system. Key methods include nasointestinal feeding, gastrostomy, and jejunostomy, each suited to different clinical scenarios based on the patient's needs and condition.
Nasointestinal Feeding
Nasointestinal feeding involves placing a tube...
Nasointestinal Feeding
Nasointestinal feeding involves placing a tube...
117
Drugs Affecting GI Tract Motility: Antimicrobials as Antidiarrheal Agents
117
Acute diarrhea, a common gastrointestinal disturbance, is characterized by the rapid evacuation of fluid stools, leading to an excessive weight in fluid. This condition typically arises from disorders affecting intestinal water and electrolyte transport. It can be triggered by an increased osmotic load within the intestine, excessive secretion of electrolytes and water, mucosal exudation of protein and fluid, or altered intestinal motility. The primary risks of acute diarrhea are dehydration...
117
Healthcare Associated Infections II: Preventive Measures
2.6K
Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
2.6K
Combined Effects of Drugs: Synergism
3.9K
Synergism is a useful mechanism where combining two or more drugs is more effective than each constituent used alone. Such combinations are also called supra-additive interactions. The drugs collectively enhance the final therapeutic effect by acting on different targets. Another advantage is that the low dose of each constituent drug is sufficient to achieve the desired effect. This helps reduce the duration of therapy and lower the adverse effects of these drugs.
Such synergistic combinations...
Such synergistic combinations...
3.9K
Enteral Nutrition I: Orogastric and Nasogastric Feeding
254
Enteral nutrition delivers nutrients directly to the stomach or small intestine through a tube. This method is appropriate for patients who cannot eat but still have a functioning digestive system. It is also beneficial for individuals with swallowing difficulties, anorexia, malabsorption, or those who have undergone gastrointestinal (GI) surgery.
Orogastric (OG) and nasogastric (NG) feeding are two standard methods used for enteral nutrition. Enteral nutrition is often preferred over...
Orogastric (OG) and nasogastric (NG) feeding are two standard methods used for enteral nutrition. Enteral nutrition is often preferred over...
254


