肥胖是否是胚胎液疾病的危险因素?
Xiteng Yan1, Beth Bentley1, Jordana Schmidt-Swartz1
1Icahn School of Medicine at Mount Sinai South Nassau, Oceanside, New York, USA.
概括
孕产妇的肥胖似乎不会增加患有羊水障碍的风险,如橄水或多水. 这项研究发现,高体重指数 (BMI) 和这些妊娠并发症之间没有显著的关联.
科学领域:
- 产科和妇科 产科和妇科
- 孕产妇和胎儿医学 孕产妇和胎儿医学
- 生殖健康 生殖健康
背景情况:
- 关于肥胖在羊水障碍中的作用,存在相互矛盾的证据.
- 之前的研究缺乏关于肥胖是否独立于其他疾病影响羊水体积的确数据.
研究的目的:
- 调查怀孕后期母亲肥胖症与橄水症和多水症的发生之间的联系.
- 为了澄清体质指数 (BMI) 和异常的胎液水平之间的关系.
主要方法:
- 对961名单独怀孕的妇女进行了回顾性队列研究.
- 超声数据 (胎液指数[AFI]或最大垂直口袋[MVP]) 收集在怀孕≥36周.
- 患者按BMI分为正常,超重和肥胖类 (I,II,III) 的患者.
主要成果:
- 增加的BMI和小糖水 (P=.21) 之间没有发现显著的关联.
- 在增加BMI和多水症 (P=.66) 之间没有发现显著的关联.
- 橄水的发病率为6.2%,多水的发病率为5.6%.
结论:
- 母体BMI升高与胎液疾病没有显著联系.
- 在这个队列中,肥胖的严重程度与高脂水或多脂水的风险增加无关.
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