系统性抗生素治疗症状的牙周炎和成年人急性牙周
Anwen L Cope1, Nick Francis2, Fiona Wood3
1Dental Public Health, School of Dentistry, Cardiff University, Cardiff, UK.
The Cochrane database of systematic reviews
|May 7, 2024
概括
系统性抗生素在与外科手术相结合时,在减少牙感染的疼痛或胀方面没有显著差异. 对于没有手术的病例,需要进一步研究.
科学领域:
- 牙科 牙科是指牙科的专业.
- 传染性疾病 传染性疾病
- 药理学 药理学是指药理学的学科.
背景情况:
- 有症状的牙周炎和急性牙周留会引起严重的牙痛.
- 临床指南建议作为一线治疗,采取局部行动措施,为扩散或全身感染预留全身抗生素.
- 过度处方抗生素可能会导致抗生素耐药性.
研究的目的:
- 评估系统性抗生素的有效性,有或没有手术和止痛药,用于治疗症状的牙周炎和成人急性牙周.
主要方法:
- 随机对照试验的系统审查和元分析.
- 搜索了多个数据库,包括Cochrane口腔健康,CENTRAL,MEDLINE,Embase和CINAHL.
- 包括134名参与者的三项试验,评估疼痛,胀和不良影响.
主要成果:
- 一项试验发现克林达米辛与安慰剂之间在疼痛或胀方面没有差异,当它与症状牙牙周节炎的内牙治疗一起使用时 (低确定性证据).
- 两项试验发现,在经过内牙治疗 (非常低确定性证据) 的急性尖端或死牙中,甲和安慰剂之间疼痛或胀没有差异.
- 没有研究将系统性抗生素与安慰剂进行比较,用于这些疾病,而无需手术干预.
结论:
- 系统性抗生素在与内牙治疗相结合时,对症状性牙周炎的疼痛或胀几乎没有益处.
- 关于在没有手术的情况下治疗急性腹的氧甲基尼西林的证据非常不确定.
- 在没有手术干预的情况下,没有研究评估了这些疾病的抗生素.
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