复发性皮肤菌感染:识别和风险因素
Pegah Tamimi1, Mahsa Fattahi1, Alireza Firooz1
1Center for Research and Training in Skin Diseases and Leprosy, Tehran University of Medical Sciences, Tehran, Iran.
International journal of dermatology
|May 7, 2024
概括
反复性皮肤植物病越来越多地是由Trichophyton indotineae引起的. 类固醇使用和长时间的抗真菌治疗有助于治疗耐药性,突显了快速PCR诊断的必要性.
科学领域:
- 皮肤病学 皮肤病学
- 菌类学 菌类学是指菌类学.
- 传染性疾病 传染性疾病
背景情况:
- 反复性皮肤植物病是一个日益严重的全球健康问题.
- 已确定Trichophyton indotineae是这种新出现的真菌感染的主要致病原体.
研究的目的:
- 调查导致反复性皮肤植物病的病因因素.
- 为了评估 tinea 感染的诊断方法.
主要方法:
- 从患有 tinea 感染的患者收集了皮肤样本.
- 方法包括直接显微镜,真菌培养和聚合酶链反应 (PCR).
主要成果:
- 在T. mentagrophytes复杂分离物中发现的Trichophyton indotineae是主要的物种.
- 在T. indotineae感染中观察到更长的疾病持续时间.
- 类固醇使用与 tinea 感染有显著的关联.
- 长期使用抗真菌药物与耐药生物体的出现相关.
结论:
- 类固醇使用,T. indotineae感染和长时间的抗真菌暴露是反抗病例的关键因素.
- 直接皮肤样本PCR推用于快速和准确的诊断,以防止治疗耐药性.
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