相关实验视频

Updated: Jun 27, 2025

Intracerebroventricular and Intravascular Injection of Viral Particles and Fluorescent Microbeads into the Neonatal Brain

Intracerebroventricular and Intravascular Injection of Viral Particles and Fluorescent Microbeads into the Neonatal Brain

Published on: July 24, 2016

为Omicron BA.5感染住院的儿童的特异性和脑损伤:使用两个队列的观察性研究

Yuan-Yuan Pei¹, Hong-Li Wang², Gen-Quan Yin³

¹Clinical Data Center, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, 510623, China.

World journal of pediatrics : WJP

|May 7, 2024

概括

感染Omicron BA.5的儿童经历了更频繁和更严重的发烧和更高的温度. 接种疫苗可能会减少的频率,并建议及时降低发烧,以缓解儿科Omicron BA.5病例的症状.

科学领域:

儿童传染病儿童传染病
病毒学病毒学
神经学神经学

背景情况:

SARS-CoV-2 Omicron BA.5 变种对儿童构成风险,其具体临床表现的数据有限.
了解儿童的Omicron BA.5症状对于改善患者护理和管理至关重要.

研究的目的:

在住院儿童中分析SARS-CoV-2 Omicron BA.5感染的特定症状.
为了比较Omicron BA.5感染和非Omicron感染儿童之间的临床特征,特别是发烧性和体温.
调查疫苗接种情况与频率之间的关联,并评估严重病例中脑损伤的发生情况.

主要方法:

一项回顾性队列研究,比较了315名住院儿童患有Omicron BA.5和16744名非Omicron发烧儿童.
分析发烧期间的率,频率和体温.
评估疫苗接种状态,疫苗剂量和发作频率之间的相关性.
在严重的Omicron BA.5病例中对大脑损伤的评估.

主要成果:

与非Omicron感染儿童相比,感染Omicron BA.5的儿童的率 (97.5%对4.3%) 和频率 (中位数为2.0对1.6) 显著更高.
患有Omicron BA.5感染的儿童在期间的体温显著更高 (中位数为39.5°C与38.2°C和38.6°C相比).
接种疫苗的儿童 (1.8) 与未接种疫苗的儿童 (2.1),发作频率较低,接种疫苗剂量和频率之间存在显著的相关性. 在112例严重病例中,有15例出现脑损伤.

结论:

在儿童中,SARS-CoV-2 Omicron BA.5 感染与发烧性的频率和严重程度增加以及温度升高有关.
疫苗似乎可以减少儿科Omicron BA.5病例的发作频率.
在严重的Omicron BA.5感染中出现脑损伤的证据强调了需要及时控制发烧和潜在的预防措施的必要性.

关键词:

身体温度身体温度大脑损伤脑损伤孩子孩子孩子孩子抽抽是一种抽.欧米克朗BA.5是什么意思疫苗接种疫苗接种

更多相关视频

A Pediatric Concussion Model in Mice: Closed Head Injury with Long-Term Disorders (CHILD)

A Pediatric Concussion Model in Mice: Closed Head Injury with Long-Term Disorders (CHILD)

Published on: February 7, 2025

Controlled Cortical Impact Model for Traumatic Brain Injury

Controlled Cortical Impact Model for Traumatic Brain Injury

Published on: August 5, 2014

相关概念视频

Seizures: Classification

Seizures: Classification

Epilepsy is primarily characterized by unpredictable seizures, either provoked by an identifiable factor, such as injury or illness, or unprovoked, occurring spontaneously without apparent cause.
Seizures are typically classified into two main categories: focal and generalized seizures.
Focal Seizures
Focal seizures originate from specific regions of the brain. These seizures are further sub-classified into two types:

Teratogenicity

Teratogenicity

The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...