在荷兰的MSM中使用长效注射PrEP的意图和偏好:创新方法的传播
Haoyi Wang1,2, Hanne M L Zimmermann1,3, David van de Vijver2
1Department of Work and Social Psychology, Maastricht University, Maastricht, Netherlands.
AIDS care
|May 7, 2024
概括
长效注射性暴露前预防 (LAI-PrEP) 是荷兰与男性发生性关系的男性 (MSM) 非常想要的. LAI-PrEP可能有利于那些有坚持问题的患者,但可能不会显著增加整体艾滋病毒预防覆盖率.
科学领域:
- 公共卫生 公共卫生
- 预防艾滋病毒 预防艾滋病毒
- 青少年和生殖健康问题
背景情况:
- 长效注射性暴露前预防 (LAI-PrEP) 证明了在与男性发生性关系的男性 (MSM) 中预防艾滋病毒的有效性.
- 预计LAI-PrEP即将在欧洲上市,因此需要了解其潜在的普及.
- 以前的研究集中在MSM之间的口服暴露前预防 (PrEP).
研究的目的:
- 调查荷兰的MSM中对LAI-PrEP的意图和偏好.
- 探索创新理论传播对LAI-PrEP采用的影响.
- 确定与LAI-PrEP在MSM中兴趣和意图相关的因素.
主要方法:
- 横截面研究设计嵌入在2017年关于口服PrEP使用的队列研究中.
- 在2022年6月对309名MSM进行调查,评估对LAI-PrEP的认识,兴趣,意图和偏好.
- 分析包括早期采用者,当前口服PrEP使用者和以前使用PrEP或停止使用PrEP的个人之间的比较.
主要成果:
- 在接受调查的MSM中报告了使用LAI-PrEP的高度兴趣 (83%) 和意图 (63%).
- 没有观察到"重复创新者效应";早期采用者没有表现出对LAI-PrEP的意图增加.
- 在目前的口服PrEP使用者中,低于最佳的坚持与偏好LAI-PrEP相关,但不打算使用它.
结论:
- 一种有效,易于获得和负担得起的LAI-PrEP可能会在荷兰得到很好的欢迎.
- 引入LAI-PrEP可能不会大幅扩大PrEP的总体覆盖范围.
- LAI-PrEP可能对MSM特别有利,MSM经历了口服PrEP的低于最佳的坚持.
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