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Updated: Jun 27, 2025

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波萨可纳醇纳米晶体固体分散的开发:制备,表征和体内评估

Ranga Goud Rayapolu1,2, Balvant Yadav2, Shashank S Apte2

  • 1Birla Institute of Technology and Science (BITS) Pilani, Hyderabad Campus, Shameerpet, Hyderabad, Telangana, India.

Pharmaceutical development and technology
|May 7, 2024
PubMed
概括

这项研究开发了一种新型纳米晶体固体分散 (NCS) 的波萨可纳 (PCZ) 来增强口服生物可用性. 优化的PCZ-NCS配方显著改善了大鼠的药物溶解性,溶解和药物动力学参数.

关键词:
波萨可纳 (Posaconazole) 是一种可靠的药物.生物可用性 生物可用性欧德拉吉特 S100 欧德拉吉特 S100高压均质化器 高压均质化器纳米晶体是一种纳米晶体.

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