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Updated: Jul 17, 2026

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使用分子动力学模拟的新德里金属β-乳糖酶-1抑制剂的约束性选择性分析:探索解码抗微生物耐药性的可能性

Shafiul Haque1, Faraz Ahmad2, Darin Mansor Mathkor3

  • 1Research and Scientific Studies Unit, College of Nursing and Health Sciences, Jazan University, Jazan 45142, Saudi Arabia; Gilbert and Rose-Marie Chagoury School of Medicine, Lebanese American University, Beirut, Lebanon.

Journal of infection and public health
|May 7, 2024
PubMed
概括

与其他测试的配体相比,N1G对新德里金属β-乳糖酶-1 (NDM1) 具有更高的结合亲和力. 这项计算研究确定了NDM1抑制的关键残留物,有助于开发新的抗菌素耐药性治疗方法.

关键词:
抗生素耐药性 抗生素耐药性在状的中.有关联体的连接体分子动力学分子动力学新德里金属β-lactamase 1 (NDM1) 的使用情况

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