肌功能障碍:从诊断到治疗的定义不佳的疾病
Brittany N Krekeler1,2,3, Rebecca J Howell4
1Department of Otolaryngology-Head & Neck Surgery, University of Cincinnati College of Medicine, Cincinnati, USA.
概括
肌功能障碍 (CPMD) 缺乏明确的诊断标准和对其病理生理学的理解. 需要进一步的研究来改善这种常见的吞障碍的诊断和治疗.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 语音语言病理学 语言病理学
- 胃肠病学 胃肠病学
背景情况:
- 喉肌肉功能障碍 (CPMD) 是一个常见的临床问题,影响吞的安全性和效率.
- 据估计,有25%的食障碍患者可能会经历一定程度的CPMD.
- 管理往往需要一个多学科的方法,包括喉科专家,语音语言病理学家和胃肠病学家.
研究的目的:
- 审查关于CPMD的当前知识.
- 识别CPMD诊断和治疗的研究缺口.
主要方法:
- 关于CPMD的概述,其相关的治疗方法和相关疾病.
- 讨论改善临床护理的未来研究方向.
主要成果:
- 详细介绍了CPMD的历史背景,病理生理学和当前的治疗实践.
- 审查强调了对CPMD潜在机制的有限理解.
结论:
- 由于对其病理生理学的理解不足以及缺乏共识的诊断标准,CPMD的定义很差.
- 未来的临床试验对于澄清CPMD发生率,其口腔喉吞影响以及最佳治疗策略至关重要.
- 进一步的研究应该集中在手术和语音语言病理学为CPMD指导的治疗方法.
相关概念视频
Chronic Pharyngitis
1.9K
Chronic pharyngitis refers to persistent inflammation of the pharyngial mucosa.
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...
1.9K
Esophageal Strictures-II: Clinical Features and Management
67
Patients with esophageal strictures often experience a range of symptoms. Initially, they may have difficulty swallowing solid foods, which can progress to include liquids. Additional symptoms may involve chest pain or discomfort, regurgitating food and fluids, heartburn, unintentional weight loss, coughing or choking during meals, and hoarseness.
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
Healthcare providers should gather a comprehensive medical history and conduct a physical examination for diagnosis. If esophageal stricture is...
67
Trachea
2.0K
The trachea, commonly known as the windpipe, is a vital part of the human respiratory system. It serves as a passageway for air to travel between the larynx and the bronchi, allowing oxygen to reach the lungs. Let's explore its anatomical features, dimensions, layers of the tracheal wall, associated muscles, and the functions of its parts.
Anatomical Features:
Location: About half of the trachea is situated in the neck, anterior to the esophagus, and extends from the larynx (at the level of...
Anatomical Features:
Location: About half of the trachea is situated in the neck, anterior to the esophagus, and extends from the larynx (at the level of...
2.0K
Gastroesophageal Reflux Disease II: Clinical Features and Management
72
Gastroesophageal reflux disease, or GERD, is a persistent medical condition that affects many individuals worldwide. Its clinical manifestations can vary greatly, making diagnosis and management challenging for healthcare professionals. The following is a comprehensive overview of the clinical manifestations, assessment, and management strategies for GERD.
Clinical Manifestations
GERD presents itself in a multitude of ways, with symptoms varying from person to person. The hallmark symptoms are...
Clinical Manifestations
GERD presents itself in a multitude of ways, with symptoms varying from person to person. The hallmark symptoms are...
72
Barrett Esophagus-II: Clinical Manifestations and Management
141
Individuals with Barrett's esophagus are often asymptomatic, but they may experience symptoms commonly associated with GERD, such as heartburn and acid regurgitation. Additional symptoms can include difficulty swallowing, chest pain, unintentional weight loss, blood in the stool (which may appear black, tarry, or bloody), and episodes of vomiting.
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure...
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure...
141
Myasthenia Gravis: Overview and Treatment
1.4K
Myasthenia gravis is a neuromuscular transmission disorder characterized by weakness and increased fatigability of skeletal muscles. It is an autoimmune disease affecting approximately one in 2000 people, where antibodies against the α1 subunit of nicotinic acetylcholine receptors are produced.
These antibodies interfere with the function of the nicotinic receptors in three ways: by binding to the receptor and disrupting acetylcholine binding; by causing cross-linking of receptors which...
These antibodies interfere with the function of the nicotinic receptors in three ways: by binding to the receptor and disrupting acetylcholine binding; by causing cross-linking of receptors which...
1.4K


