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肥胖患者减肥手术后多维生素支持的有效性:一项前性观察性研究
Alessio Basolo1, Susanna Bechi Genzano1, Jacopo Vitti1
1Obesity and Lipodystrophy Center, Endocrinology Unit, University Hospital of Pisa, 56124, Pisa, Italy.
Eating and weight disorders : EWD
|May 7, 2024
概括
腹腔外科手术患者服用Bariatrifast手术后没有出现维生素缺乏. 这种维生素和矿物质配方有效地保持了必需营养水平,并且耐受性很好.
科学领域:
- 腹部外科 腹部外科
- 营养科学 营养科学
- 内分泌学 在内分泌学.
背景情况:
- 减肥手术 (BS) 对严重肥胖有效,但可能导致微量营养素缺乏.
- 监测和预防这些缺陷对于患者的治疗结果至关重要.
研究的目的:
- 评估一种特定的维生素/矿物质配方Bariatrifast在预防和治疗BS后微量营养素缺乏症的有效性.
- 评估巴利亚特里法斯特在巴利亚特外科手术后患者的安全性和耐受性.
主要方法:
- 对20名患者进行垂直袖子胃切除术 (VSG) 或Roux-en-Y胃绕道 (RYGB) 的前性观察性研究.
- 营养水平 (费里丁,叶酸,维生素B12,,维生素D,PTH) 在手术前和手术后1,3,6和12个月被测量.
- 患者在BS后每天接受口服巴里亚特里法斯特补充剂.
主要成果:
- 在所有患者中都观察到显著的体重减轻.
- 在整个研究期间,没有发现微量营养素缺乏.
- 血清中维生素B12,25-OH维生素D和叶酸的水平在手术后增加.
- 与RYGB患者相比,VSG患者在某些时间点显示出更高的维生素D,B12和叶酸水平.
- 没有报告任何不良事件.
结论:
- 在VSG或RYGB.后的患者中,巴里亚特里法斯特的使用维持了正常的必需微量营养素水平.
- 补充剂被很好地容忍,没有胃肠道副作用.
- 这种配方支持营养管理,遵循减肥程序.
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