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评估玻璃眼中饮用水测试的价值 - - 一个系统的审查和元分析

Eric Jin¹, Claire Xin Yi Goh¹, Bjorn Kaijun Betzler^1,2

¹Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.

Eye (London, England)

|May 7, 2024

概括

饮用水测试 (WDT) 显示了与格劳科马患者的昼间眼内压力 (IOP) 监测有很强的相关性. WDT峰值IOP是可重现的,可以预测未来的视野损失.

科学领域:

眼科医生眼科眼科
玻璃眼研究研究玻璃眼研究
诊断工具诊断工具诊断工具

背景情况:

眼内压力 (IOP) 监测对于玻璃眼病管理至关重要.
饮用水测试 (WDT) 是评估IOP动态的一个潜在工具.
WDT的可复制性和预测值需要进一步研究.

研究的目的:

系统地审查和元分析WDT衍生的IOP参数和日间IOP监测之间的关系.
为了评估WDT的可复制性.
评估WDT结果与未来的玻璃眼视野 (VF) 损失之间的关联.

主要方法:

在PubMed,EMBASE和Cochrane图书馆的系统文献搜索,截至2023年3月31日.
包括队列,横截面和观察性研究,报告绿眼病患者的WDT结果.
使用随机效应模型的元分析与R.中的"metafor"包.

主要成果:

在WDT的峰值IOP和白天监测之间发现了强烈的正相关性 (r=0.92).
在WDT和白天监测之间观察到IOP波动的弱正相关性 (r=0.26).
较高的WDT峰值IOP与未来更大的VF进展相关;WDT峰值IOP显示出良好的可重现性.

结论:

WDT峰值IOP测量与日间IOP监测在玻璃眼中有很强的相关性.
WDT是一种可重复的IOP评估测试.
在WDT峰值IOP可能作为未来视野进展的预测器在青光眼患者.

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