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在加拿大怀孕期间患有糖尿病
Chantal Rm Nelson1, Susie Dzakpasu2, Aideen M Moore3
1Maternal and Infant Health Section, Centre for Surveillance and Applied Research, Public Health Agency of Canada, 785 Carling Ave, Ottawa, ON, Canada. chantal.nelson@phac-aspc.gc.ca.
BMC pregnancy and childbirth
|May 7, 2024
概括
糖尿病 (DM) 率,包括妊娠期 (GDM),1型 (T1DM) 和2型 (T2DM),在加拿大怀孕中显著增加. 这一趋势与更高的母亲和婴儿不良结果率有关.
科学领域:
- 生殖健康 生殖健康
- 内分泌学 在内分泌学.
- 公共卫生监督 公共卫生监督
背景情况:
- 关于加拿大怀孕期间糖尿病 (DM) 患病率的当代数据很少.
- 本研究调查了15年来加拿大1型糖尿病 (T1DM),2型糖尿病 (T2DM) 和妊娠期糖尿病 (GDM) 的趋势.
- 还检查了与DM相关的选择性不良妊娠结果.
研究的目的:
- 分析加拿大怀孕中T1DM,T2DM和GDM患病率的15年趋势.
- 确定怀孕期间的DM与母亲和婴儿不良结果之间的关联.
- 为公共卫生规划提供有关怀孕期糖尿病的最新流行病学见解.
主要方法:
- 利用了加拿大卫生信息研究所 (CIHI) 从2006年到2019年的住院释放摘要数据库 (DAD) 数据.
- 将母亲分娩记录与4,320,778次分娩的出生记录联系起来.
- 计算了DM患病率,使用Cochrane-Armitage测试评估时间变化,并分析了省/地区的变化.
主要成果:
- 在为期15年的研究期间,观察到GDM,T1DM和T2DM患病率的统计学上显著增加.
- 与没有DM的怀孕相比,任何形式的DM的怀孕都表现出更高的高血压和剖腹产率.
- 婴儿不良后果,包括主要的先天性异常,早产和大孕年龄,在患有DM的怀孕中更为频繁.
结论:
- 加拿大的怀孕显示出糖尿病 (DM) 的患病率正在上升.
- 预计2型糖尿病 (T2DM) 和妊娠期糖尿病 (GDM) 将进一步增加,受母亲超重和肥胖率上升的影响.
- 这些发现凸显了加拿大管理妊娠糖尿病的日益严重的公共卫生挑战.
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