在腰椎椎间盘的患者中,基于QCT的副脊椎肌肉特性和骨矿物质密度之间的关系
Ze Li1,2, Junrong Chen3, Jian Yang2
1School of Sports Medicine and Health, Chengdu Sport University, No.2, Tiyuan Road, Chengdu, Sichuan, China.
BMC musculoskeletal disorders
|May 7, 2024
概括
在MRI上对脊椎肌肉脂肪透 (PDFF) 和横截面积 (CSA) 与腰椎间盘 (LDH) 患者的骨密度相关. 较高的PDFF和较低的CSA表明较低的体积骨矿物质密度 (vBMD),这表明骨质疏松症评估的潜在生物标志物.
科学领域:
- 放射学 放射学是一门学科.
- 整形外科 整形外科 整形外科
- 骨的新陈代谢 骨的新陈代谢
背景情况:
- 骨质疏松症的评估至关重要,而副脊髓肌肉脂肪透成为潜在的生物标志物.
- 腰椎间盘 (LDH) 患者可能会表现出改变的副脊髓肌肉特性.
- 研究LDH肌肉特征与骨密度之间的联系对于临床管理很重要.
研究的目的:
- 通过MRI评估的腰椎副脊髓肌肉特性 (横截面积和脂肪分数) 与通过QCT测量的体积骨矿物质密度 (vBMD) 之间的关系.
主要方法:
- 对383名LDH患者 (24-76岁) 的回顾性分析.
- 腰部MRI测量了多体 (MF),直立脊柱 (ES) 和大心肌 (PS) 肌肉截面面积 (CSA) 和质子密度脂肪分数 (PDFF).
- 定量CT (QCT) 测量了L1/L2的vBMD;患者分为正常,骨质疏松症和骨质疏松症组.
主要成果:
- 与正常和骨质疏松症组相比,患有骨质疏松症的患者表现出显著更高的副脊髓肌肉PDFF和较低的CSA (p < 0.001).
- 在调整年龄和性别 (p < 0.05) 后,多 PDFF 和 psoas major CSA 被确定为影响vBMD的独立因素.
结论:
- 通过MRI测量的副脊髓肌肉特性,包括PDFF和CSA,与LDH患者的vBMD有关.
- 增加的副脊髓肌肉脂肪透 (PDFF) 和减少的肌肉CSA与减少的vBMD相关.
- 这些发现表明,MRI衍生类型的副脊髓肌肉指标可以帮助评估骨密度,并为LDH患者量身定制治疗.
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