在肥胖患者中,甘油三指数与亚临床左心室缩功能障碍之间的关联
Guang-An Li1, Jun Huang2, Jing Wang3
1Department of Echocardiography, The Affiliated Changzhou Second People's Hospital with Nanjing Medical University, 213003, Changzhou, China.
Cardiovascular diabetology
|May 7, 2024
概括
甘油三糖 (TyG) 指数与肥胖个体的亚临床左心室 (LV) 缩功能障碍有关. 较高的TyG指数值表明LV全球纵向应变 (GLS) 损伤的风险更大.
科学领域:
- 心脏病学 心脏病学
- 代谢综合征是代谢综合征的一种.
- 心声回声扫描 (Echocardiography) 是一种心声回声扫描.
背景情况:
- 在肥胖患者中,甘油三糖指数 (TyG) 和亚临床左心室 (LV) 缩功能障碍之间的关系尚未得到充分证实.
- 肥胖是心血管疾病的重要危险因素,包括心脏功能受损.
- TyG指数是胰岛素抵抗的标志物,可能在心脏异常的发展中发挥作用.
研究的目的:
- 在一组肥胖患者中调查TyG指数和LV全球纵向菌株 (GLS) 之间的关联.
- 确定TyG指数是否是该人群中亚临床LV缩功能障碍的独立预测指标.
主要方法:
- 总共分析了1028名肥胖患者.
- 收集了临床,生化和心声回声数据.
- 使用心声学评估LV全球纵向应变 (GLS),并计算TyG指数.
主要成果:
- 患有高TyG指数的肥胖患者表现出高血压,糖尿病和高脂血症的更高发病率.
- 在高TyG指数组中,LV GLS明显低于低TyG指数组 (P = 0.01).
- 在多变量调整 (OR: 1.520, P = 0.031) 后,TyG指数仍然是减少LV GLS (<20%) 的独立风险指标.
结论:
- 提升的TyG指数与肥胖患者的亚临床左心室缩功能障碍独立相关.
- TyG指数可以作为一种有价值的生物标志物,用于识别患有心脏功能障碍风险的肥胖个体.
更多相关视频
06:13Author Spotlight: Exploring the Impact of Reduced Resistance Exercise Volume on Metabolic Health
Published on: December 1, 2023
1.1K
08:30Intraperitoneal Glucose Tolerance Test, Measurement of Lung Function, and Fixation of the Lung to Study the Impact of Obesity and Impaired Metabolism on Pulmonary Outcomes
Published on: March 15, 2018
14.1K
相关概念视频
01:24Obesity
468
The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in...
468
01:15Diabetes: Symptoms, Diagnosis, and Complications
526
For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
526
01:24Overview of Lipid Metabolism
1.4K
Lipid metabolism is a crucial process in the human body that involves the synthesis and degradation of lipids. This process is essential for energy production, cell membrane formation, and hormone production, among other functions.
Lipolysis: The Breakdown of Lipids:
Lipolysis is the process of breaking down lipids, particularly triglycerides, into glycerol and fatty acids. This process typically occurs in the adipose tissue and is triggered by various hormones, including glucagon and...
Lipolysis: The Breakdown of Lipids:
Lipolysis is the process of breaking down lipids, particularly triglycerides, into glycerol and fatty acids. This process typically occurs in the adipose tissue and is triggered by various hormones, including glucagon and...
1.4K