探索肉牛中汗腺特征的遗传控制,以提高耐热性
Aakilah S Hernandez1, Gabriel A Zayas2, Eduardo E Rodriguez2
1Department of Animal Science, North Carolina State University, Raleigh, NC, USA.
Journal of animal science and biotechnology
|May 7, 2024
概括
识别布朗格斯牛中耐热性遗传标记可以改善亚热带地区的生产. 这项研究发现,Brahman和Angus祖先都对汗腺特征有积极的贡献,为遗传选择提供了一条改善热耐性的途径.
科学领域:
- 动物遗传学动物遗传学
- 量化遗传学 量化遗传学
- 畜牧业生产 畜牧业生产
背景情况:
- 热应激显著限制了亚热带地区的肉牛生产,造成了相当大的经济损失.
- 热应激通过减少料摄入量和整体生产率对牛产生负面影响.
- 提高耐热性的基因选择,重点关注诸如出汗效率等特征,对于减轻这些影响至关重要.
研究的目的:
- 为了确定与布兰古斯牛的汗腺特征相关的遗传变异,以改善耐热性.
- 调查布拉曼和安格斯祖先对热耐受性特征的贡献.
主要方法:
- 使用从皮肤活检 (汗腺区域,深度,长度) 中获得的表型,对2,401头布兰古斯牛进行分析.
- 使用牛GGP F250K进行基因造型,并使用BLUPF90进行遗传参数估计和全基因组关联研究 (GWAS).
- 利用品种起源等位基因 (BOA) 预测和BOA GWAS来确定祖先对汗腺特征的贡献.
主要成果:
- 汗腺表型表现出适度的遗传性 (0.170.42),表明了选择的遗传潜力.
- 在BTA7和BTA12上,GWAS确定了与ADGRV1和CCD168基因相关的显著定量特征位点 (QTL).
- 博阿·格瓦斯 (BoA GWAS) 透露,布拉曼和安格斯等位基因对汗腺特征都有积极影响.
结论:
- 基于已识别的汗腺特征的基因选择可以增强牛的热耐受性.
- 利用来自Brahman和Angus两种品种的遗传洞察力,提供了一种改善畜牧业热量管理的策略.
- 了解这些遗传因素对于使畜牧业适应气候变化影响至关重要.
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