在需要PICC插入的恶性病患者中,系统性免疫炎症指数和DVT之间的关联
Na Li1, Jing Huang1, You Feng1
1Department of Oncology, West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, China.
Biological research for nursing
|May 8, 2024
概括
系统性免疫炎症指数如PLR,SII和SIRI与癌症患者外围插入中央导管深静脉血栓形成 (PICC-DVT) 的风险增加有关. 这些索引可以作为PICC-DVT的辅助预测测试.
科学领域:
- 在瘤学瘤学.
- 血管医学 血管医学
- 免疫学 免疫学 免疫学
背景情况:
- 周围插入的中央导管 (PICC) 对于癌症患者的化疗至关重要,以防止细胞毒剂泄漏.
- 深静脉血栓症 (DVT) 是一种已知的并发症,虽然炎症有关,但系统性免疫炎症指数在PICC-DVT中的作用尚不清楚.
研究的目的:
- 为了研究外围插入的中央导管深静脉血栓症 (PICC-DVT) 和关键的全身免疫炎症指数之间的关联.
- 具体评估的是血小板与淋巴细胞的比率 (PLR),全身免疫炎症指数 (SII) 和全身炎症反应指数 (SIRI).
主要方法:
- 在2018年8月至2021年10月期间,一组513名癌症患者接受了化疗前PICC植入,并参加了2021年10月的研究.
- 深静脉血栓症 (DVT) 是使用彩色多普勒超声波来诊断的.
- 使用后勤回归分析来确定相关性.
主要成果:
- 在513名患者中,57名 (11.1%) 患有PICC-DVT.
- 升高的PLR (p = .014),SII (p = .012) 和SIRI (p = .022) 与PICC-DVT显著相关.
- 这些指数的较高值表明发展PICC-DVT的可能性更大.
结论:
- 系统性免疫炎症指数与外围插入的中央导管深静脉血栓症 (PICC-DVT) 的风险增加有关.
- 这些指数显示出潜在的辅助预测标记,用于识别患有PICC-DVT风险较高的患者.
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