相关实验视频

Updated: May 5, 2026

The Multiple Sclerosis Performance Test MSPT: An iPad-Based Disability Assessment Tool

The Multiple Sclerosis Performance Test MSPT: An iPad-Based Disability Assessment Tool

Published on: June 30, 2014

复发性复发性多发性硬化症患者的认知表型与不同的疾病持续时间,应用国际认知障碍的MS分类 (IC-CoDiMS)

Cláudia Sousa^1,2,3, Teresa Jacques², Márcia França³

¹Department of Neurology, Centro Hospitalar Universitário São João Porto, EPE, Alameda Prof. Hernâni Monteiro, Porto, Portugal.

The Clinical neuropsychologist

|May 8, 2024

概括

使用IC-CoDiMS的复发性转发性多发性硬化症 (RRMS) 患者中识别认知表型揭示了认知障碍的独特模式,有助于向治疗.

科学领域:

神经科学是一个神经科学.
临床神经学临床神经学
心理学心理学心理学

背景情况:

认知障碍影响多发性硬化症 (MS) 患者的40-70%,主要影响信息处理速度和记忆.
目前对认知障碍的二分类分类 (受损与未受损) 限制了对异质多发性硬化群体中特定认知领域变化的理解.
在MS认知障碍国际分类 (IC-CoDiMS) 为详细的认知表型提供了一个框架.

研究的目的:

使用IC-CoDiMS在患有复发性复发性硬化症 (RRMS) 的成年患者中识别认知表型.
描述与RRMS中识别的认知表型相关的临床特征.
完善认知表型的分类,以改善治疗和干预开发.

主要方法:

一组300名RRMS患者接受了全面的神经心理评估.
评估包括神经心理测试的简要重复电池 (BRBN-T) 和简要国际认知多发性硬化症 (BICAMS).
在-1 SD和-1.5 SD值时,使用IC-CoDiMS标准确定认知表型.

主要成果:

在 -1 SD 值时,49%的人在认知上是完整的,25%的人具有单域,17%的双域和9%的多域损伤.
处理速度是 -1 SD 最常见的单域损伤,其次是记忆和语言流性.
在-1.5 SD值时,74.7%的人在认知上是完整的,具有单域 (17%),双域 (6%) 和多域 (3%) 的障碍;记忆是最常见的单域障碍.

结论:

这项研究验证了IC-CoDiMS在RRMS中确定认知表型的实用性.
表型化增强了RRMS患者认知变化的分类.
改进的分类支持开发更有效的治疗方法和认知干预措施,用于MS相关的认知障碍.

关键词:

认知表型认知表型认知表型简要国际认知评估多发性硬化症简短的重复电池神经心理测试多发性硬化症多发性硬化症神经心理评估神经心理评估

更多相关视频

A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data

A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data

Published on: December 9, 2015

Comprehensive Autopsy Program for Individuals with Multiple Sclerosis

Comprehensive Autopsy Program for Individuals with Multiple Sclerosis

Published on: July 19, 2019

相关概念视频

Language and Cognition

Language and Cognition

Language serves as a bridge between ideas and communication, influencing how individuals perceive and interact with the world. Psychologists have long debated whether language shapes thought or vice versa. This discussion gained grip with Edward Sapir and Benjamin Lee Whorf in the 1940s, who proposed that language determines thought, a concept known as linguistic determinism. They suggested that the vocabulary and structure of a language influence how its speakers think and perceive reality.

Cognitive Development During Adulthood

Cognitive Development During Adulthood

Cognitive development continues throughout adulthood, undergoing significant shifts across early, middle, and late stages. Individual transition occurs from adolescent idealism to pragmatic and adaptable thinking in early adulthood. During this period, individuals learn to integrate personal beliefs with the recognition that other perspectives are equally valid. Exposure to the complexities of modern society, diverse experiences, and higher education contribute to this adaptive thought process,...

Multiple Sclerosis l: Introduction

Multiple Sclerosis l: Introduction

Multiple sclerosis is a chronic autoimmune disease of the central nervous system (CNS) that affects the brain, spinal cord, and optic nerves. It is an inflammatory demyelinating disorder and a leading cause of neurological disability in young adults.EpidemiologyMS commonly begins between 20 and 40 years of age and is twice as common in women. Its exact cause remains unclear, but genetic susceptibility contributes, with higher risk in first-degree relatives and identical twins. A greater...