GRIN2A

Daisy G Y Thompson-Lake1, Frederique J Liegeois1, Ruth O Braden1

  • 1From the WVU Department of Neuroscience (D.G.Y.T.-L.), West Virginia University School of Medicine, Rockefeller Neuroscience Institute, Morgantown, WV; UCL Great Ormond Street Institute of Child Heath (D.G.Y.T.-L., F.J.L.), London, UK; Speech and Language (R.O.B., L.M., M.H., A.T.M.), Murdoch Children's Research Institute; Florey Institute of Neuroscience and Mental Health (G.D.J., I.E.S.), Parkville; Department of Community and Clinical Health (S.J.T.), La Trobe University, Bundoora; Department of Medicine (M.H.), University of Melbourne; Department of Paediatrics (R.O.B., I.E.S.), University of Melbourne, Royal Children's Hospital Parkville; Department of Audiology and Speech Pathology (I.E.S., A.T.M.), University of Melbourne, Parkville; and Department of Medicine (I.E.S.), University of Melbourne, Austin Hospital, Heidelberg, Australia.

PubMed
概括

致病性GRIN2A变体与-失语综合征 (EASs) 有关,导致言语和语言缺陷. 脑部成像显示了变化的大脑周边区域,特别是布罗卡区域,以及受影响个体的左海马体积减少.