药物对维护血液透析患者跌倒风险评估的影响:一个横截面研究
Raghad M Ismail1, Dixon Thomas1, Rajaram Jagdale2,3
1Department of Pharmacy Practice, College of Pharmacy, Gulf Medical University, Ajman, United Arab Emirates.
概括
药物因素显著影响血液透析患者的跌倒风险,掩盖与年龄相关的差异. 消除这些因素揭示了老年人中较高的跌倒风险,突出了药物治疗.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學.
- 老年病的医生 老年病的医生
- 临床药房 临床药房
背景情况:
- 末期脏病 (ESKD) 患者接受血液透析 (HD) 面临多因素跌倒风险.
- 已知年龄,性别和透析持续时间是导致该人口中跌倒风险的因素.
- 药物对ESKD患者跌倒风险解释的特定影响仍未得到充分研究.
研究的目的:
- 调查药物因素如何影响血液透析患者跌倒风险的评估.
- 为了确定药物是否会影响与年龄,性别和透析持续时间相关的跌倒风险的解释.
- 确定药物在ESKD患者中跌倒风险年龄相关差异中的作用.
主要方法:
- 一项截面研究于2023年在阿联阿杰曼的第三级护理学术医疗中心进行.
- 使用约翰·霍普金斯秋季风险评估工具进行数据收集.
- 分析了44名血液透析患者的跌倒风险数据,比较了不同年龄组,性别和透析持续时间的药物因素和无药因素的评估.
主要成果:
- 跌倒风险评估最初没有显示年龄组之间的显著差异 (P = 0.43).
- 删除药物因素显示了跌倒风险的显著差异 (P = 0.002),特别是在46-60岁和60岁以上的年龄组之间 (P < 0.001).
- 当排除药物因素时,在年龄和跌倒风险之间发现了中等的正相关性 (r = 0.514,P < 0.001);性别和透析持续时间没有显著的关联.
结论:
- 药物因素对血液透析患者的跌倒风险有很大影响.
- 药物数据可以掩盖与年龄相关的跌倒风险差异,特别是在中年和老年人之间.
- 药物对跌倒风险的影响是特定于年龄的,不扩展到这一群体的性别或透析持续时间.
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