通过疫苗接种预防宫癌:审查
Julio Cesar González-Rodríguez1, Aurelio Cruz-Valdez2, Vicente Madrid-Marina3
1Department of Oncology Gynecology, Instituto Nacional de Cancerología (INCAN), México City, Mexico.
Frontiers in oncology
|May 8, 2024
概括
人类乳头瘤病毒 (HPV) 疫苗接种计划在预防HPV相关疾病方面取得了显著的成功,长期有效性和安全性得到证明. 持续监测对于全球宫癌根除工作至关重要.
科学领域:
- * 瘤学 在线咨询
- * 疫苗学 疫苗学 疫苗学
- * * 公共卫生 公共卫生
背景情况:
- * 全球范围内建议青少年进行例行人类乳头瘤病毒 (HPV) 疫苗接种.
- *尽管有建议,但HPV疫苗接种计划的有效性仍然低于最佳水平,影响了宫癌根除目标.
研究的目的:
- *对HPV疫苗计划的有效性,长期保护和安全性进行文献审查.
- *描述全球HPV疫苗接种计划的现状,并评估双价,四价和非价预防性HPV疫苗的长期结果.
- * 专注于来自不同国家的现实有效性数据.
主要方法:
- *关于HPV疫苗接种的已发表研究的综合文献综述.
- *对疫苗疗效,剂量和真实世界的有效性数据的分析.
- *包括关于HPV疫苗长期免疫性和安全性的证据.
主要成果:
- * 强有力的HPV疫苗接种计划的国家报告HPV相关疾病的显著减少,包括高度宫异常和生殖器 (54%-83%).
- *HPV疫苗的长期疗效高达9.4年,具有持续的免疫性和出色的安全性.
- *全球HPV疫苗覆盖率不均,高收入国家和低收入国家之间存在差异.
结论:
- *HPV疫苗接种计划在预防疾病方面取得了显著的成功.
- * 长期有效性和安全性数据支持继续使用HPV疫苗.
- *为实现公共卫生目标,建立持续监测HPV疫苗免疫性,有效性和安全性的系统至关重要.
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