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Updated: Jun 26, 2025

Biosensor-based High Throughput Biopanning and Bioinformatics Analysis Strategy for the Global Validation of Drug-protein Interactions
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在实验室中确定乙氨基对蛋白的共价结合的位点占用率

Timon Geib1, Cristina Lento2, Vanessa Marensi3

  • 1Chemistry Department Université du Québec à Montréal Montréal Canada.

Analytical science advances
|May 8, 2024
PubMed
概括

乙氨基的毒性源于NAPQI与蛋白质结合. 一种新的LC-MS/MS方法量化了这种与GST等特定蛋白质的结合,揭示了修饰部位并协助了毒性研究.

关键词:
N-乙p-本佐基诺因 imine 的使用.乙氨基的使用方法谷氨酸S-转移酶的使用.多重反应监测多重反应的监测.蛋白质共价结合的共价结合.蛋白质的修改 蛋白质的修改反应性代谢物反应性代谢物网站占用情况 网站占用情况

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