为患有急性COVID-19的儿童开非推药物的处方模式
Julianne E Burns1, Alex Dahlen2, Laura L Bio3
1Divisions of Infectious Diseases.
Pediatrics
|May 8, 2024
概括
尽管率较低,但未经建议的COVID-19药物被处方给儿童,强调需要明确的指导. 了解这些处方模式对于保护儿童健康至关重要.
科学领域:
- 儿童传染病 儿童传染病
- 药物监督 药物监督 药物监督
- 公共卫生政策 公共卫生政策
背景情况:
- 尽管有反对其使用的证据,但针对COVID-19的重用药物被处方.
- 国家指导方针不鼓励在急性COVID-19中使用某些药物.
研究的目的:
- 确定儿童急性COVID-19非推药物的处方率.
- 确定与这些处方相关的人口因素和提供者类型.
- 分析国家指南建议不使用的时期的处方趋势.
主要方法:
- 使用美国大型全付款人索赔数据库进行回顾性队列研究.
- 对2020年3月至2022年12月期间被诊断患有COVID-19的18岁以下儿童的分析.
- 多变量后勤回归用于识别处方风险因素.
主要成果:
- 在不推的时间内,Hydroxychloroquine (HCQ) 和ivermectin分别在0.03%和0.14%的儿科COVID-19病例中被处方.
- 处方率因州而异,阿肯色州 (HCQ) 和俄克拉荷马州 (ivermectin) 的处方率更高.
- 高龄,非公共保险,急诊室访问,非城市和低收入地区与处方风险增加有关;全科医生处方率最高.
结论:
- 虽然处方率很低,但COVID-19的高负担导致了许多对儿童的不有效和潜在有害的处方.
- 了解过度使用模式是减轻错误信息及其后果的关键.
- 向提供者和家长传播明确的,基于证据的建议对于儿科健康至关重要.
更多相关视频
09:36Halogenated Agent Delivery in Porcine Model of Acute Respiratory Distress Syndrome via an Intensive Care Unit Type Device
Published on: September 24, 2020
2.8K
08:36Author Spotlight: Evaluating the Adjuvant Efficacy and Safety of Angong Niuhuang Pill in Viral Encephalitis Treatment
Published on: April 19, 2024
499
相关概念视频
01:02Prescription, Nonprescription and Orphan Drugs
721
Prescription drugs require a prescription from a medical practitioner and can only be obtained from a pharmacy. They have many applications, including treating pain, anxiety, and hypertension.
The misuse and addiction to prescription drugs is a growing problem that can affect people of all age groups, specifically teenagers. This can happen when prescription medications are used in ways not intended by the prescriber, such as taking someone else's prescription or using medication for...
The misuse and addiction to prescription drugs is a growing problem that can affect people of all age groups, specifically teenagers. This can happen when prescription medications are used in ways not intended by the prescriber, such as taking someone else's prescription or using medication for...
721
01:30Asthma-IV: Diagnostic and Management
2.5K
The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
2.5K
01:21Factors Affecting Drug Response: Overview
2.0K
When it comes to infants and young children, they are typically administered smaller doses of medication in comparison to adults. This is primarily because their organ functions still need to fully develop, meaning their bodies are not as efficient at metabolizing or eliminating drugs. Additionally, their blood-brain barrier is more permeable than in adults. As a result, high concentrations of drugs can easily penetrate the central nervous system (CNS), potentially leading to neurological...
2.0K
01:28Pneumonia IV: Management
323
The treatment of pneumonia varies based on its severity and the causative pathogen. Here is a structured approach to managing pneumonia, integrating pharmaceutical and supportive care strategies.
Bacterial Pneumonia Treatment
For bacterial pneumonia, antibiotics serve as the cornerstone of therapy. Initial treatment often begins with empirical antibiotics, tailored to the anticipated causative organism and adjusted based on culture results. Key antibiotic choices include:
Bacterial Pneumonia Treatment
For bacterial pneumonia, antibiotics serve as the cornerstone of therapy. Initial treatment often begins with empirical antibiotics, tailored to the anticipated causative organism and adjusted based on culture results. Key antibiotic choices include:
323
01:17Drugs Used in Lower Respiratory Disorders: Overview
424
Lower respiratory tract disorders present challenges that often require skilled and nuanced approaches for effective management. Common ailments, such as asthma and chronic obstructive pulmonary disease (COPD), have prompted the development of intricate treatment strategies involving bronchodilators and anti-inflammatory drugs, each tailored to ease breathing and revitalize the lungs.
Bronchodilators, the first step of respiration enhancement, come in various forms, each with its own mechanism...
Bronchodilators, the first step of respiration enhancement, come in various forms, each with its own mechanism...
424
01:25Drug Classes and Categories
2.0K
Drugs can be classified according to their chemical composition or their intended therapeutic application. For instance, anti-infective agents that possess the ability to eliminate pathogens or suppress their growth and reproduction can be grouped based on the organisms they target or their chemical structure. Furthermore, drugs can be divided into prescription, nonprescription, or controlled substances. Prescription medications, such as antibiotics, require oversight from a licensed healthcare...
2.0K