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Updated: Jul 2, 2026

Detection of MicroRNA Expression in the Kidneys of Immunoglobulin A Nephropathic Mice
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跨物种单细胞分析揭示了与IgA瘤病变进展相关的免疫病理机制

Xizhao Chen1, Tiantian Wang1, Lei Chen2

  • 1Department of Nephrology, The First Medical Center of Chinese People's Liberation Army General Hospital, Nephrology Institute of the Chinese People's Liberation Army, State Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Beijing Key Laboratory of Kidney Disease Research, Beijing, China.

JCI insight
|May 8, 2024
PubMed
概括

IgA脏病 (IgAN) 涉及特定的细胞相互作用,特别是介质细胞和巨细胞之间的相互作用,由炎症途径驱动. 阻断CXCL12/CXCR4通路在Igan模型中显示有望减少损伤和改善功能.

关键词:
自身免疫性疾病是一种自身免疫性疾病.这是一种自身免疫力.生物信息学是一种生物信息学.化学因子 (chemokines) 是一种化学物质.免疫学 免疫学 免疫学

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