在SARS-CoV-2感染或人类连续接种疫苗后对mRNA疫苗接种的先天免疫反应的调节

Fredrika Hellgren1,2, Anja Rosdahl3,4, Rodrigo Arcoverde Cerveira1,2

  • 1Division of Immunology and Allergy, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden & Karolinska University Hospital, Stockholm, Sweden.

JCI insight
|May 8, 2024
PubMed
概括

之前的SARS-CoV-2感染增强了对mRNA疫苗的天生的免疫反应,在初始剂量后增加了炎症和免疫细胞活性. 这种由现有的免疫驱动的效应突显了先前感染如何塑造疫苗反应.

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