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Updated: Jun 26, 2025

Induction of Maternal Immune Activation in Mice at Mid-gestation Stage with Viral Mimic PolyI:C
07:13

Induction of Maternal Immune Activation in Mice at Mid-gestation Stage with Viral Mimic PolyI:C

Published on: March 25, 2016

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在体外mRNA-S母体疫苗接种诱导了母胎界面的免疫调节变化

Ananth Kumar Kammala1, Madhuri Tatiparthy1, Tilu Jain Thomas1

  • 1Division of Basic Science and Translational Research, Department of Obstetrics & Gynecology, The University of Texas Medical Branch at Galveston, Galveston, Texas, USA.

American journal of reproductive immunology (New York, N.Y. : 1989)
|May 8, 2024
PubMed
概括

母亲mRNA-S疫苗接种可能会改变母胎界面的免疫环境. 这项研究研究了mRNA-S疫苗和含有Spike (S) 蛋白质的细胞外囊泡 (EVs) 在怀孕期间对免疫细胞的影响.

关键词:
这是mRNA疫苗.怀孕和母亲与胎儿之间的接口.尖端蛋白质是指尖端蛋白质中的一个.

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Development of Immunocompetence01:22

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The initiation of cell-mediated immunity can be observed as early as the third month of fetal growth, with active antibody-mediated immunity following approximately one month later.
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
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Genomic Imprinting and Inheritance

Diploid organisms inherit genetic material through chromosomes from both parents. Copies of the same gene are known as alleles. In most cases, both alleles are simultaneously expressed and allow various cellular processes to function optimally. If one of the alleles is missing or mutated, the expression of the other allele can compensate; however, this is not true for all genes.
The expression of some genes depends on which parent passed the gene to the offspring, through a phenomenon known as...
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