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饮食遵守和缓解是否减少了乳患者的氧化应激?

Berat Ebik¹, Ferhat Bacaksiz¹, Ali Uzel¹

¹University of Health Sciences, Diyarbakır Gazi Yasargil Education and Research Hospital, Division of Gastroenterology - Diyarbakır, Turkey.

Revista da Associacao Medica Brasileira (1992)

|May 8, 2024

概括

达到乳性疾病的缓解改善了硫化-硫化的稳态,这表明氧化应激减少了. 不遵守无质饮食会加剧腹患者的炎症和氧化应激.

科学领域:

生物化学生物化学
免疫学免疫学免疫学
胃肠病学胃肠病学

背景情况:

病是一种自身免疫性疾病,由摄入质引发.
不遵守无质饮食会导致慢性炎症和氧化应激.
二硫化物恒温是氧化应激和炎症的标志物.

研究的目的:

为了研究缓解状态对乳二硫化物恒温的影响,在患有乳病的患者.
评估氧化应激和炎症在乳性疾病不合规性中的作用.
作为疾病活动的间接指标,建立二硫化物恒温.

主要方法:

这是一项前性,随机的,受控的研究,涉及117名乳病患者.
血液样本在基线和一年后收集,以测量醇和二硫化物.
此外,还监测了常规的乳病测试和抗组织转质氨酶IgA水平.

主要成果:

55.6%的患者没有缓解,而44.4%的患者实现了缓解.
实现缓解的患者表现出本源醇水平增加 (p=0.001) 和二硫化物水平降低 (p<0.001).
在进入缓解期的患者中,减少的二硫化物水平和减少的抗组织转质氨酶IgA之间观察到显著的相关性 (r=0.526;p<0.001).

结论:

缺乏缓解的乳性疾病与增加的氧化压力有关.
二硫化物稳态作为氧化应激和炎症的间接标记在乳病中.
达到缓解有效地降低了胆固醇患者的氧化应激.

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