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Updated: Jul 2, 2026

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通过GFP表达寄生虫改善体外查化合物抗Trypanosoma cruzi

Cleyson Mathias Morais Delvoss1,2, Alexandre Haruo Inoue2, Rosiane Valeriano da Silva2

  • 1Universidade Estadual de Ponta Grossa, Laboratório de Biologia Celular e Protozoologia, Ponta Grossa, PR, Brasil.

Memorias do Instituto Oswaldo Cruz
|May 8, 2024
PubMed
概括

使用GFP表达的Trypanosoma cruzi (Tc-GFP) 的新光方法为评估抗寄生虫药物对细胞内巨的疗效提供了比微观计数更快的替代方案.

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American Trypanosomiasis01:22

American Trypanosomiasis

Chagas disease, or American trypanosomiasis, is a vector-borne parasitic infection caused by Trypanosoma cruzi, a flagellated protozoan (kinetoplastid) of the family Trypanosomatidae. The disease is endemic in Latin America, although cases are increasingly reported worldwide due to human migration. Transmission most commonly occurs when feces of infected triatomine bugs contaminate bite wounds or mucosal surfaces; additional routes include congenital, transfusional, transplant-related, and oral...