生物相容的基于铜的纳米复合材料用于联合癌症治疗
Yibo Song1, Kok Bing Tan1, Shu-Feng Zhou1
1College of Chemical Engineering, Academy of Advanced Carbon Conversion Technology, Huaqiao University, 668 Jimei Avenue, Xiamen, 361021 Fujian, P. R. China.
ACS biomaterials science & engineering
|May 8, 2024
概括
基于铜 (Cu) 和Cu的纳米材料在癌症治疗方面表现有前途. 本综述探讨了用于联合疗法的集成Cu-纳米复合体,讨论了挑战和未来的临床转化.
科学领域:
- 纳米医学和材料科学 纳米医学和材料科学
- 瘤学和癌症治疗学 癌症治疗学
背景情况:
- 基于铜 (Cu) 和Cu的纳米材料具有独特的物理化学特性和生物相容性,使它们成为治疗疾病,特别是癌症的吸引力.
- 现有的研究已经开发出各种基于Cu的纳米复合物用于各种癌症治疗,包括化疗,放射治疗 (RT),光热疗法 (PTT),化学动力疗法 (CDT),光动力疗法 (PDT) 和cuproptosis介导疗法.
研究的目的:
- 审查基于Cu的纳米材料在癌症治疗中的当前研究环境.
- 讨论基于Cu的纳米复合体在联合癌症治疗策略中的应用.
- 确定这些纳米治疗平台的临床转化当前的挑战和未来的前景.
主要方法:
- 对用于癌症治疗的基于Cu的纳米材料的研究进行了全面的文献综述.
- 基于Cu的集成纳米复合物的分析及其治疗方式.
- 讨论联合治疗方法,包括化疗,RT,PTT,CDT,PDT和cuproptosis.
主要成果:
- 基于Cu的纳米材料为开发先进的癌症疗法提供了多功能平台.
- 结合多种治疗方式的集成纳米复合体显示出增强抗癌疗效的巨大潜力.
- 复合纳米系统的开发对于下一代纳米药物至关重要.
结论:
- 基于Cu的纳米复合体代表了创新的癌症治疗策略的有希望的途径.
- 使用这些纳米复合体的联合治疗方法对于克服单一治疗方法的局限性至关重要.
- 解决临床翻译方面的挑战是实现基于Cu的纳米治疗药物的全部潜力的关键.
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