在儿科电子诊断研究中的口服和局部止痛
Bisma Aziz1, Sajid Hameed2, Haris Hakeem3
1Department of Medicine, Aga Khan University Hospital, Karachi, Pakistan.
Muscle & nerve
|May 8, 2024
概括
结合口服和局部止痛药 (COTA) 在电肌图 (EMG) 过程中,在年幼的儿童中减轻了疼痛. 然而,对于儿科神经传导研究 (NCS) 和EMG的整体疼痛管理需要进一步调查.
科学领域:
- 儿科神经生理学儿童神经生理学
- 疼痛管理 疼痛管理
- 临床试验 临床试验
背景情况:
- 诸如神经导电研究 (NCS) 和针式肌电图 (EMG) 等电子诊断检查通常被儿童认为是痛苦的.
- 有效的疼痛减轻策略对于改善患者的服从性至关重要,并且可以产生神经认知和神经精神病学的好处.
研究的目的:
- 评估联合口服和局部止痛药 (COTA),口服止痛药 (OA) 和安慰剂在儿童患者NCS/EMG期间减轻疼痛的疗效.
- 为了比较不同止痛干预和不同年龄组的疼痛评分.
主要方法:
- 进行了一项双盲,随机,安慰剂对照试验,涉及接受NCS/EMG的儿科患者.
- 参与者被分为两个年龄组 (6个月6岁和718岁) 并分配到COTA,OA或安慰剂手臂.
- 使用修改行为疼痛量表 (MBPS) 和面部疼痛量表修订 (FPS-R) 来评估疼痛.
主要成果:
- 在结合年龄组时,在NCS和EMG的所有干预臂中,没有观察到监护人报告的疼痛得分 (FPS-R) 的显著差异.
- 在7-18岁儿童的NCS中,OA和安慰剂组之间发现了疼痛严重程度分布的显著差异 (p=0.007).
- 电磁图谱手术总是比NCS更痛苦 (p<0.05). 在6个月6岁的儿童中,当EMG期间至少采集了10个肌肉样本时,COTA显著降低了疼痛评分 (p=0.014).
结论:
- 在NCS/EMG期间儿童的疼痛感知是复杂的,这表明需要加强疼痛管理策略.
- 程序性因素,如EMG期间采样的肌肉数量,可以影响止痛效果.
- 需要进一步的研究来优化儿科电子诊断程序的疼痛管理协议.
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