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人类肝脏阿尔德氧化酶的原生性:对药物代谢的发育变化和影响

Sandhya Subash1, Dilip K Singh1, Deepak Ahire1

  • 1College of Pharmacy and Pharmaceutical Sciences, Washington State University (WSU), Spokane, Washington 99202, United States.

Molecular pharmaceutics
|May 8, 2024
PubMed
概括

甲基氧化酶 (AO) 含量和活性从出生到成年期在人类肝细胞中显著增加. 这种AO的发育变化对于预测儿童药物代谢至关重要.

关键词:
阿尔德海德氧化酶的使用.药物代谢 药物代谢人类的本体生长过程 (ontogeny)定量化的蛋白质组学.

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