使用Liljestrand和Zander公式计算心脏输出量:这种方法是否适用于出生后的过渡期? - 一个事后 hoc 分析
Daniel Pfurtscheller1,2,3, Bernhard Schwaberger1,2,3, Nina Höller1,2,3
1Division of Neonatology, Department of Pediatrics and Adolescent Medicine, Medical University of Graz, Auenbruggerplatz 34/2, 8036, Graz, Austria.
在出生后评估新生儿心脏输出 (CO) 是至关重要的. 利尔杰斯特兰德和桑德公式 (COest/adj LaZ) 与电气生物阻抗 (CO-生物阻抗) 具有很高的可比性,为新生儿的CO测量提供了一种可行的方法.
科学领域:
- 新生儿生理学 新生儿生理学
- 心血管过渡的发生.
- 医疗器械技术 医疗器械技术
背景情况:
- 在出生后立即评估新生儿的心血管过渡是关键的,但具有挑战性.
- 心声图,非侵入性心力输出 (CO) 评估的黄金标准,在立即新生儿过渡期间的可行性有限.
- 电气生物阻抗和Liljestrand和Zander公式为CO评估提供了潜在的非侵入性替代方案.
研究的目的:
- 为了比较调整的估计心脏输出值 (COest/adj LaZ) 与在出生后的过渡期内在新生儿中非侵入性测量的心脏输出值 (CO-生物阻抗).
- 评估两个非侵入性方法的可行性和可比性,以评估新生儿心脏输出.
主要方法:
- 一项涉及早产和满产新生儿的前性观察研究的二次结果分析.
- 在出生后10分钟和15分钟测量动脉血压和心率.
- 使用电气生物阻抗 (CO-生物阻抗) 进行非侵入性心脏输出测量,并使用Liljestrand和Zander公式计算COest/adj LaZ.
主要成果:
- 包括32名新生儿,他们的妊娠年龄中位数为37.0周.
- 平均CO-生物阻抗为0.62 ± 0.15 L/分钟,平均COest/adj LaZ为0.64 ± 0.10 L/分钟.
- 在COest/adj LaZ和CO-bioimpedance (p=0.025,r=0.359) 之间发现了显著的相关性.
结论:
- 经过调整的Liljestrand和Zander公式 (COest/adj LaZ) 显示了在立即过渡期间与新生儿的电气生物阻抗 (CO-生物阻抗) 的高可比性.
- 这些发现表明,COest/adj LaZ提供了一种具有成本效益和可行的方法,用于在其他方法无法使用时获得心脏输出.
- 非侵入性CO测量方法对于监测新生儿心血管适应是有价值的.
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