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Updated: Jun 26, 2025

A Quantitative Measurement of Reactive Oxygen Species and Senescence-associated Secretory Phenotype in Normal Human Fibroblasts During Oncogene-induced Senescence
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A Quantitative Measurement of Reactive Oxygen Species and Senescence-associated Secretory Phenotype in Normal Human Fibroblasts During Oncogene-induced Senescence

Published on: August 12, 2018

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氧化DNA损伤促进了与细胞外矩阵调节蛋白的变化相关的血管衰老

Kirsty Foote1, Marieke Rienks2, Lukas Schmidt2

  • 1Section of Cardiorespiratory Medicine, University of Cambridge, Victor Phillip Dahdaleh Heart & Lung Research Institute, Papworth Road, Cambridge Biomedical Campus, Cambridge CB2 0BB, UK.

Cardiovascular research
|May 8, 2024
PubMed
概括

氧化性DNA损伤有助于血管衰老和硬化. 基切除修复酶8-Oxoguanine DNA Glycosylase (Ogg1) 对此进行保护,调节细胞外矩阵蛋白质.

关键词:
年龄化 衰老 衰老造成的DNA损伤是DNA损伤.细胞外矩阵是细胞外矩阵.

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