代谢功能障碍相关的脂肪肝疾病的生活方式干预:一个24小时的综合行为视角
Shelley E Keating1, Yogesh Chawla2, Arka De3
1School of Human Movement and Nutrition Sciences, The University of Queensland, Brisbane, QLD, Australia. s.keating@uq.edu.au.
Hepatology international
|May 8, 2024
概括
生活方式干预是管理代谢功能障碍相关脂肪肝疾病 (MAFLD) 的关键. 包括饮食,运动和睡眠在内的24小时综合方法为MAFLD患者提供了显著的健康益处.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 代谢疾病 代谢疾病
- 生活方式 医学 医疗
背景情况:
- 与代谢功能障碍相关的脂肪肝病 (MAFLD) 构成了日益严重的全球健康和经济挑战.
- 生活方式干预对于管理MAFLD和相关心脏代谢疾病至关重要.
研究的目的:
- 审查支持MAFLD生活方式管理策略的证据.
- 强调对MAFLD的24小时综合行为方法.
- 为实施基于证据的生活方式变化提供实际建议.
主要方法:
- 对现有关于MAFLD生活方式干预的文献进行系统审查.
- 对聚焦饮食,体育活动,久坐行为,睡眠,吸烟和酒精摄入量的研究进行分析.
- 综合24小时行为模型的评估.
主要成果:
- 7-10%的减肥是有益的,但改善饮食质量和运动甚至在没有减肥的情况下也会带来好处.
- 建议采取综合的24小时生活方式,包括饮食,体育活动,减少久坐时间和充足的睡眠.
- 强烈支持地中海饮食和每周150-240分钟的中度至强度有氧运动;抵抗训练对特定人群有益.
结论:
- 为了实现可扩展的医疗整合,还需要进行更多的大规模,多学科的试验,并进行长期跟踪.
- 未来的指导方针必须解决MAFLD异质性,并促进协调,专业的护理模式.
- 开发新的,可访问的生活方式干预措施可以克服行为改变的障碍.
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