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Updated: Jun 26, 2025

Following in Real Time the Impact of Pneumococcal Virulence Factors in an Acute Mouse Pneumonia Model Using Bioluminescent Bacteria
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Published on: February 23, 2014

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在产后发育期间上呼吸道屏障功能受损会导致侵袭性肺炎球菌病的发生

Kristen L Lokken-Toyli1, Surya D Aggarwal1, Gavyn Chern Wei Bee1

  • 1Department of Microbiology, New York University School of Medicine, New York, New York, United States of America.

PLoS pathogens
|May 8, 2024
PubMed
概括

婴儿小鼠由于上呼吸道 (URT) 屏障功能受损,对Streptococcus pneumoniae (Spn) 感染的易感性增加. 这种脆弱性,以延迟的粘膜干净和改变的紧结基因表达为特征,在生命早期促进了细菌的传播和血液传播.

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