E-PROOF:蛋白质摄入和抵抗训练的电子干预以优化功能:一个研究协议
Jessica L Krok-Schoen1, Zachary L Chaplow2, Cara Chase1
1School of Health and Rehabilitation Sciences, College of Medicine, The Ohio State University, Columbus, OH, United States of America.
PloS one
|May 8, 2024
概括
这项研究测试了一项在线计划,将营养和抵抗训练相结合,用于老年癌症幸存者,以改善身体功能和生活质量. 通过E-PROOF干预,该群体的健康行为和结果有望得到改善.
科学领域:
- 老年学是指老年学的学科.
- 在瘤学瘤学.
- 运动生理学 运动生理学
背景情况:
- 老年癌症幸存者 (≥65岁) 与同龄人相比,面临身体功能损害的风险高2-5倍.
- 身体功能下降显著影响生活质量和独立性在这个人口.
- 有针对性的干预措施对于减轻癌症及其治疗对健康的长期影响至关重要.
研究的目的:
- 评估E-PROOF (蛋白质摄入和抵抗训练以优化功能) 研究的可行性,可接受性和初步疗效.
- 评估12周的在线定制营养和抵抗训练干预对身体功能的影响.
- 检查对老年癌症幸存者的肌肉力量,与健康相关的生活质量 (HRQoL),自我效能和体重管理的影响.
主要方法:
- 一个为期12周的随机对照试验,涉及70名老年癌症幸存者.
- 实验组接受了远程行为咨询和定制教育;对照组接受了一般生存教育.
- 干预对身体功能,肌肉强度,HRQoL,自我效能,体重和腰围的影响进行测量,随访3个月.
主要成果:
- 该研究旨在提供关于干预措施在改善关键身体和健康结果方面的有效性的初步数据.
- 分析将在12周的干预期和随访期间比较实验组和对照组之间的变化.
- 可行性和可接受性数据将为未来的大规模试验提供信息.
结论:
- 这是针对老年癌症幸存者进行的首次同步,在线的以蛋白质为重点的饮食和抵抗训练干预.
- 该研究促进了独立的健康行为,并为可扩展的在线干预提供了基础知识.
- 预计这些发现将推进改善癌症幸存者的健康状况的策略.
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