在糖尿病患者的光学一致性断层扫描血管图形中血管变化的种族/种族分析
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Abu Tahir Taha1,2, Yi Stephanie Zhang1,2, Isabel J B Thompson1
1Department of Ophthalmology, University of California, San Francisco, California, USA.
Ophthalmic epidemiology
|May 8, 2024
概括
与白人患者相比,种族和民族少数群体表现出明显的视网膜微血管差异,特别是在深层毛细血管中,无论其社会经济地位如何. 这些发现突出了糖尿病视网膜病变结果的潜在差异.
科学领域:
- 眼科医生 眼科 眼科
- 医疗成像医学成像
- 血管生物学 血管生物学
背景情况:
- 糖尿病视网膜病变 (DR) 不成比例地影响种族和少数民族.
- 少数群体经常出现DR的更先进阶段.
- 了解微血管差异对于解决健康差异至关重要.
研究的目的:
- 为了研究种族/族群之间的光学连贯性断层扫描血管学 (OCTA) 的微血管差异.
- 分析糖尿病人和非糖尿病人的这些差异.
- 评估社会经济地位 (SES) 对这些微血管变化的影响.
主要方法:
- 斑点OCTA扫描 (3x3mm2) 分析了状血管区域 (FAZ) 面积和周围.
- 表面 (SCP) 和深层毛细管 (DCP) 血管密度 (VD),血管长度密度 (VLD) 和调整的流量指数 (AFI) 被量化.
- 多变量回归模型调整为SES使用面积剥夺指数.
主要成果:
- 与NH白患者相比,西班牙裔,亚裔和黑人患者的FAZ区域和周长显著增加.
- 这些群体也表现出较低的DCP船舶密度和长度密度.
- 社会经济地位并没有显著改变观察到的微血管差异.
结论:
- 在种族/民族少数群体和NH白患者之间存在显著的视网膜微血管差异,无论SES.
- 这些差异在深层毛细管中尤其明显.
- 这些发现表明,糖尿病视网膜病变的结果可能更差,眼科护理差异更大.
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